Search results for " Salvia"

showing 10 items of 15 documents

Marginalia in tema di pignus conventum

2020

Discussing a recent book on the subject of pignus conventum, the author makes some exegetical observations and interpretative hypotheses on the history of this institution and its judicial protection.

interdictum Salvianuminvecta et illataPignus conventumSettore IUS/18 - Diritto Romano E Diritti Dell'Antichita'
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Synthetic studies of neoclerodane diterpenoids from Salvia splendens and evaluation of opioid receptor affinity

2008

Abstract Salvinorin A ( 1 ), a neoclerodane diterpene from the hallucinogenic mint Salvia divinorum , is the only known non-nitrogenous and specific κ-opioid agonist. Several structural congeners of 1 isolated from Salvia splendens ( 2 – 8 ) together with a series of semisynthetic derivatives ( 9 – 24 ), some of which possess a pyrazoline structural moiety ( 9 , 19 – 22 ), have been tested for affinity at human μ, δ, and κ opioid receptors. None of these compounds showed high affinity binding to these receptors. However, 10 showed modest affinity for κ receptors suggesting that other natural neoclerodanes from different Salvia species may possess opioid affinity.

AgonistbiologyChemistrymedicine.drug_classStereochemistryOrganic ChemistryPyrazolineSalviabiology.organism_classificationBiochemistryArticleSalvinorin Achemistry.chemical_compoundOpioid receptorClerodanes opioid receptors salviaDrug DiscoverySalvia divinorummedicineDiterpeneReceptor
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Clerodane diterpenoids from Salvia splendens.

2006

Four new clerodane diterpenoids, salvisplendins A-D (1-4), have been isolated from an acetone extract of the flowers of SalVia splendens, together with an artifact (5), arising from salvisplendin D (4) by addition of diazomethane, and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and, in the case of salvisplendin A (1), by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6), not published hitherto, are also reported.

StereochemistryPharmaceutical ScienceFlowersSalviaAnalytical ChemistryDiterpenes Clerodanechemistry.chemical_compoundFour new clerodane diterpenoids salvisplendins A-D (1-4) have been isolated from an acetone extract of the flowers of SalVia splendens together with an artifact (5) arising from salvisplendin D (4) by addition of diazomethane and the already known clerodane olearin (6). The structures of the new compounds (1-5) were established mainly by 1D and 2D NMR spectroscopic studies and in the case of salvisplendin A (1) by chemical correlation with splenolide B (7). Complete 1H and 13C NMR assignments for olearin (6) not published hitherto are also reportedDrug DiscoveryOrganic chemistrySalviaNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalbiologyMolecular StructureChemistryDiazomethaneOrganic ChemistryCarbon-13 NMRbiology.organism_classificationChemical correlationTerpenoidComplementary and alternative medicineItalyMolecular MedicineDiterpeneTwo-dimensional nuclear magnetic resonance spectroscopyLactoneJournal of natural products
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Considerazioni sulle strutture edilizie dell'area del Tempio-Criptoportico

2013

Il contributo si prefigge lo scopo di analizzare le emergenze architettoniche dell'area del Tempio-Criptoportico, centro cultuale della città romana di Urbs Salvia. Il grande complesso sntuariale venen eretto in età tiberiano-claudia al di sopra di un quartiere abitativo di notevole pregio che si affacciava sul lato orientale del Foro della città. Un poderoso Criptoportico fungeva da sostegno ad un Tempio esastilo corinzio, del quale oggi restano solo scarni resti del podio, circondato da un portico su tre lati. Lo studio propone una ipotesi ricostruttiva del complesso e delle sue fasi di vita.

Architettura RomanaTempioCriptoporticoSantuariodomuUrbs Salvia
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Involvement of Bax and Bcl-2 in induction of apoptosis by essential oils of three Lebanese Salvia species in human prostate cancer cells

2018

Prostate cancer is one of the most common forms of cancer in men, and research to find more effective and less toxic drugs has become necessary. In the frame of our ongoing program on traditionally used Salvia species from the Mediterranean Area, here we report the biological activities of Salvia aurea, S. judaica and S. viscosa essential oils against human prostate cancer cells (DU-145). The cell viability was measured by 3(4,5-dimethyl-thiazol-2-yl)2,5-diphenyl-tetrazolium bromide (MTT) test and lactate dehydrogenase (LDH) release was used to quantify necrosis cell death. Genomic DNA, caspase-3 activity, expression of cleaved caspase-9, B-cell lymphoma 2 (Bcl-2) and Bcl-2 associated X (Ba…

Male0301 basic medicineSalvia miltiorrhiza<i>Salvia</i>; essential oil; prostate cancer; apoptosis; reactive oxygen specieslcsh:ChemistryProstate cancer0302 clinical medicineSalvialcsh:QH301-705.5Spectroscopybcl-2-Associated X Proteinreactive oxygen speciesCamphanesapoptosisGeneral Medicineprostate cancerComputer Science ApplicationsGene Expression Regulation NeoplasticProto-Oncogene Proteins c-bcl-2030220 oncology & carcinogenesisApoptosis Essential oil Prostate cancer Reactive oxygen species SalviaProgrammed cell deathSalvia; apoptosis; essential oil; prostate cancer; reactive oxygen speciesPanax notoginsengDNA FragmentationBiologyArticleCatalysisessential oilInorganic Chemistry03 medical and health sciencesBcl-2-associated X proteinCell Line TumorOils VolatilemedicineHumansViability assayPhysical and Theoretical ChemistryMolecular BiologyCell ProliferationCell growthOrganic ChemistryProstatic NeoplasmsCancerSettore CHIM/06 - Chimica Organicamedicine.diseaseapoptosi030104 developmental biologylcsh:Biology (General)lcsh:QD1-999ApoptosisCancer cellCancer researchbiology.proteinDrugs Chinese Herbal
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Anti-tumor activity of the methanolic extracts of Salvia menthifolia

2012

In the present research we investigated the anti-proliferative activity of Salvia menthifolia Ten. (formerly Salvia menthaefolia), Lamiaceae, on a glioblastoma cell line, since up to date poor therapeutic results have been reported for treatment of malignant glioblastoma. Methanol extracts from different anatomical parts of S. menthifolia were tested on DBTRG-05MG cell line by MTT assay. The most active primary stems extract was also evaluated for apoptosis induction. Results confirmed the anti-tumor property of all the organs and demonstrated that the primary stems extract induced apoptosis after 4 h with the highest values of DNA fragmentation after 6 to 24 h. Some extracts were also HPLC…

lcsh:RS1-441Salvialcsh:Pharmacy and materia medicachemistry.chemical_compoundapoptosis glioblastoma Salvia menthifolia sageCaffeic acidMTT assaySettore BIO/15 - Biologia FarmaceuticaGeneral Pharmacology Toxicology and Pharmaceuticsapoptosis; glioblastoma; Salvia menthifolia; sageapoptosis glioblastomabiologyTraditional medicineRosmarinic acidapoptosisglioblastomaSalvia menthifoliabiology.organism_classificationQuercitrinSettore CHIM/08 - Chimica FarmaceuticasagechemistryBiochemistryPolyphenolSettore BIO/03 - Botanica Ambientale E ApplicataDNA fragmentationLamiaceae
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Essential oils of Salvia bracteata and Salvia rubifolia from Lebanon: Chemical composition, antimicrobial activity and inhibitory effect on human mel…

2009

Aim of the study: Salvia bracteata Banks et Sol. and Salvia rubifolia Boiss. are known in folk medicine of Lebanon for the treatment of microbial infections, cancer, urinary and pulmonary problems. In the present study the chemical composition and antimicrobial activity of essential oils from aerial parts of Salvia bracteata and Salvia rubifolia collected in Lebanon were evaluated. The oils were also tested for their potential antiproliferative effects against M14 human melanoma cells. Material and methods: The oils were studied by GC and GC-MS and their antibacterial activity (MIC and MBC) was tested against ten bacteria species using the broth dilution method. The inhibitory effect on hum…

Cell SurvivalApoptosisDNA FragmentationMicrobial Sensitivity TestsAntiproliferative activityAntimicrobial activitySalviaPharmacognosyGram-Positive BacteriaEssential oillaw.inventionlawCell Line TumorDrug DiscoveryOils VolatileHumansMTT assaySalviaLebanonMedicinal plantsMelanomaEssential oilCell ProliferationPharmacologybiologyTraditional medicinePlant ExtractsCell MembraneSalvia bracteataAntimicrobial activity Antiproliferative activity Essential oil Salvia bracteata Salvia rubifoliabiology.organism_classificationAntimicrobialAntineoplastic Agents PhytogenicAnti-Bacterial AgentsComet assaySalvia rubifoliaAntibacterial activityPhytotherapyJournal of Ethnopharmacology
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Il foro di Pollentia-Urbs Salvia

2017

Pollentia-Urbs SalviaPollentia-Urbs Salvia Urbanistica ScavoUrbanisticaScavo
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The «Painted» Hypogeum of Crispia Salvia (Marsala-TP) ‒ 2nd Century C.E. Preliminary Anthropological and Archaeological Report of Tomb 3 and Tomb 4

2021

Summary ― The «Painted Hypogeum of Crispia Salvia» is the most important monument of the ancient Punic-Roman necropolis of Lilibeo (today's Marsala). It is the only known paradigmatic example in Sicily of pictorial wall decoration. Iulius Demetrius commissioned the monument in memory of his wife Crispia Salvia, a noblewoman descended from two very important Sicilian families. Here we report on a preliminary anthropological study of Tombs 3 and 4 (Crispia Salvia and Iulius Demetrius). We integrated the historical-cultural context with the osteological data. The results combining laboratory and archaeological research confirm the presence of two high-ranking individuals characterized by condi…

AnthropologyLilibeumCrispia salviaSettore BIO/08 - Antropologia
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Chemical composition and anticancer activity of essential oil of Mediterranean sage (Salvia officinalis L.)

2013

Anticancer activity essential oil Salvia officinalis L.Settore CHIM/06 - Chimica OrganicaSettore BIO/15 - Biologia Farmaceutica
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